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正高級(jí)

  • 姓名： 張磊
  • 性別： 男
  • 職稱： 研究員
  • 職務(wù)： 
  • 學(xué)歷： 博士
  • 電話： 027-87199105
  • 傳真： 
  • 電子郵件： leizhang@apm.ac.cn
  • 所屬部門： 磁共振影像研究部
  • 通訊地址： 湖北省武漢市洪山區(qū)中國(guó)科學(xué)院精密測(cè)量與技術(shù)創(chuàng)新研究院波譜樓2002

    簡(jiǎn)　　歷：

  • 學(xué)習(xí)經(jīng)歷?

    2007年09月-2011年06月??四川大學(xué) 學(xué)士?
    2012年09月-2017年08月??美國(guó)德克薩斯大學(xué)達(dá)拉斯分校 博士?
    工作經(jīng)歷?
    2018年01月-2021年08月??中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所 副研究員?
    2021年08月-至今??中國(guó)科學(xué)院精密測(cè)量與技術(shù)創(chuàng)新研究院 研究員

    社會(huì)任職：

    研究方向：

  • 小分子磁共振造影劑的研發(fā)及活體應(yīng)用

    承擔(dān)科研項(xiàng)目情況：

    代表論著：

  • 1) Haonan He, Long Xiao, Kelu Zhao, Yi Zhang, Yi Cheng, Shizhen Chen, Lei Zhang,* Xin Zhou* and Kai Liu*, Hongjie Zhang. Detection and chiral recognition of α‐hydroxyl acid through proton and CEST NMR using Yb macrocyclic complex. Angew Chem Int Edit. 2019., 58,18286 –18289?

    2) Lei Zhang？ , André F. Martins？ , Piyu Zhao, Michael Tieu, David Esteban-Gómez, Gregory T. McCandless, Carlos Platas-Iglesias and A. Dean Sherry*. Enantiomeric recognition of D- and L-lactate by CEST with the aid of a paramagnetic shift reagent. J Am Chem Soc 2017, 139(48): 17431~17437?
    3) Lei Zhang？ , André F. Martins？ , Piyu Zhao, Yunkou Wu, Gyula Tircso, Dean Sherry*. Lanthanide-based T2ex and CEST complexes provide new insights into the design of pH sensitive MRI agents. Angew Chem Int Edit. 2017.12.4, 56(52): 16626~16630?
    4) Lei Zhang？ , André F. Martins？ , Yuyan Mai, Piyu Zhao, Alexander Funk, M. Veronica Clavijo Jordan, Shanrong Zhang, Wei Chen, Yunkou Wu and A. Dean Sherry*. Imaging extracellular lactate in vitro and in vivo using CEST MRI and a paramagnetic shift reagent. Chem-Eur J, 2017, 23 (8), 1752.?
    5) Lei Zhang*; Jingjing Li; Kai Liu*, Recent advances in gadolinium-based MRI metal responsive agent, SCI China Technol SC, 2018.7.13, 61(9): 1329~1333
    6) Yi Zhang, Kelu Zhao, Haonan He, Sikang Wan, Andre F. Martins, Lei Zhang*and Kai Liu. A T2ex MRI Dy-based contrast agent for direct pH imaging using a ratiometric approach. Dalton Trans.2021,50, 2014-2017?
    7) Sikang Wan, Fengzhi Cui, Bo Li, Kelu Zhao, Haonan He, Yi Zhang, Jianhua Liu, Lei Zhang*, and Kai Liu*. Dysprosium-Modified Gold Nanoparticles as T2ex Contrast Agents for Magnetic Resonance Imaging. ACS Appl. Nano Mater. 2020, 3, 9, 9433–9439
    8) Yibin Yu, Yi Cheng, Junye Tong, Lei Zhang*, Yen Wei, Mei Tian. Recent advances in thermo-sensitive hydrogels for drug delivery. J. Mater. Chem. B, 2021,9, 2979-2992?
    9) Yang Liu, Wenyao Zhen, Yinghui Wang, Jianhua Liu, Longhai Jin, Tianqi Zhang, Songtao Zhang, Ying Zhao, Na Yin, Rui Niu, Shuyan Song, Lei Zhang, and Hongjie Zhang. Double Switch Biodegradable Porous Hollow Trinickel Monophosphide Nanospheres for Multimodal Imaging Guided Photothermal Therapy Nano Lett.2019, 198, 5093-5101?
    10) Chao Ma, Jing Sun, Bo Li, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert G？stl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu & Andreas Herrmann. Nat Commun .(2021) 12:3613

    專利申請(qǐng)：

    獲獎(jiǎng)及榮譽(yù)：

  • 2022年入選武漢英才計(jì)劃